Jenny is desperate to shed her Brooklyn past as she feels obligated to fulfill her role in becoming queen of the Upper East side—regardless of compromising friendships and morals. Eric and Jonathan end their relationship due to Eric's change in character. Dan and Vanessa attempt to accomplish a list of college experiences (including a threesome) in hopes that Olivia (Hilary Duff) doesn't leave NYU for a new movie. Olivia receives a text that the movie has been canceled as the three lay in bed together. Blair and Serena's friendship is repaired as Serena confesses she had sought out her estranged father, and failed doing so. Serena and Tripp may become more than just friends.[28]
Title comes from the 1969 movie "They Shoot Horses, Don't They?"